Meanwhile, glutathione is a tripeptide consisting of cysteine, glycine, and glutamate that functions as a major antioxidant and is involved in cellular detoxification for the maintenance of the skin cell environment
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On the other hand, similar DNA protective action has been found also in the case of other polyphenols, e.g., quercetin, that decreased the levels of 8-hydroxydeoxyguanosine in kidney or liver cells following their exposure to oxidative stress 157,158,159
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While most evidence points to an invasion from the Mediterranean at the end of the 19 th century 21 , an earlier invasion of the Pacific Islands from the Americas is plausible, given historical records of arboviral disease outbreaks in Southeast Asia 61 and early outbreaks of dengue in New Caledonia specifically 60
