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It may be helpful in treating or preventing heart and blood vessel conditions, diabetes, gum disease, muscular dystrophy, chronic fatigue syndrome, and breast cancer

By contrast, phenformin exhibits a higher lipophilicity than metformin, owing to its larger phenylethyl side chain, and is therefore crossing more easily lipid membrane bilayer, a property that might explain their differences in terms of selectivity and potency

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In cells with PRMT1 overexpression or PRMT5 knockdown, it was further confirmed that overexpression of PRMT1 following chemotherapy suppressed the protein level of PRMT5 (Fig

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