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6 Polysaccharides regulate the gut microbiota Natural polysaccharides are widespread biological macromolecules that function as structural components, energy reserves, and protective agents in diverse organisms

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This has been reported with both tirzepatide and retatrutide, though it is likely related to the weight loss itself rather than the medication directly

Thiolation of Q295: site-specific conjugation of hydrophobic payloads without the need for genetic engineering

Cell Death and Stress Cell death can result from different pathways, and oxidative stress can be an upstream trigger