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Chronic inflammation can contribute to oxidative stress and deplete Glutathione

increased urinary medium-chain acylcarnitines indicate localized renal dysfunction [157, 158]

The content is solely the authors responsibility and does not necessarily represent the official views of the National Institutes of Health

The signs are similar to those of S

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However, despite the widespread nature of this condition, there are no internationally standardised guidelines regarding dosage regimes, optimal formulation, frequency of administration of B12 therapy and monitoring of therapeutic effect, leading to significantly variable international practice (Andres and Serraj, 2012