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As part of the antioxidant defence system, GSH participates in conjugation reactions catalyzed by glutathione-S-transferases (GSTs), in the reduction of hydrogen peroxide (H O ) and lipid hydroperoxides (LOOH) catalyzed by glutathione peroxidases (Gpxs), and the reduction 2 2 of protein-disulfi des (PrSSG) catalyzed by glutaredoxins (Grxs)

This protein, often overexpressed on the membranes of certain cancer cells, plays a critical role in the progression of malignancies

doi: 10.1210/me.11.13.1924

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We placed a twin-strep tag on the N- or C-terminal of MXRA8 and tested its feasibility as an indicator of E protein binding