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MELD-3 improvement in HCC patientsincluding within Cluster two where HCC prevalence was 34.9% likely reflects tumour-directed therapies or fluctuations in hepatic reserve unrelated to antioxidant supplementation, and should not be interpreted as evidence of glutathione efficacy

Duffin R, Gilmour PS, Schins RP, Clouter A, Guy K, Brown DM, MacNee W, Borm PJ, Donaldson K, Stone V

Reduced production of peroxided lipids and induction of iron overload were observed in an ACSL4 conditional deletion mouse, conversely, the phenotype was reversed upon overexpression of ACSL4

[DOI] [PubMed] [Google Scholar] Luo C, Ding W, Yang C, Zhang W, Liu X, Deng H

Cell stress & chaperones

Tsc1 regulates tight junction independent of mTORC1