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Collagen supplements are generally considered safe and are associated with few negative side effects when used as directed

That said, in published research to date, melanotan II administration has produced minor side effects such as fatigue, nausea, and yawning, and has not been associated with serious adverse events when administered to healthy subjects

We prescribe skin lightening tablets over systemic IV infusions as supplements are much safer

Buisset, A

Schriefer D, et al

Cortisol is a stress hormone that, when chronically elevated, promotes fat storage (particularly visceral fat), breaks down muscle tissue, impairs sleep, and suppresses immune function