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10.1016/j.jare.2020.07.007 50 YanL

41 A complementary mechanism involves cardiolipin-mediated mitophagy, in which cardiolipin externalizes to the outer mitochondrial membrane and directly interacts with LC3 to trigger mitochondrial turnover

Male Wistar rats (180-240 g b.w.) have been used for this experiment

SPINE 30 (21), 23792387

FOXO4-DRI appears to work by inhibiting FOXO4-p53 binding

To predict the potential risks inherent to the surgical procedures, a preoperative brain MRI should be performed to check for the presence of brain atrophy and/or other organic lesions