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Chronic stress affects hormone levels, including cortisol, which can trigger inflammatory responses in the body

10.6004/jadpro.2020.11.2.1 80 WangL.QinY.WangY.LiuB.ZhouY

Herein, we describe a long-term high-throughput microfluidic liver chip for studying chronic liver diseases compatible with standard laboratory automation technologies

Activation of mitochondrial voltage-dependent anion channels and mitogen-activated protein kinases, upregulation of endoplasmic reticulum stress, and inhibition of cystine/glutamate antiporter is involved in the induction of ferroptosis

Four of the identified compounds have mutagenic potential (AMES negative) namely compounds 1 (Methyl methanethiolsulfonate), 13 (S-Methyl methanethiosulphonate), 26 (2-Methoxy-4-vinylphenol), and 29 (2-(hydroxymethyl)-2-nitro-1,3-)

Uemura N, Marotta NP, Ara J, Meymand ES, Zhang B, Kameda H, et al