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A mitochondrial enzyme CARS2 generates cysteine persulfide from cysteine, which is regarded as one of the major processes for production of persulfides, i.e., molecular species containing more than one sulfur atoms in thiol moiety

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Efficacy and safety of oral deucravacitinib in patients with cutaneous manifestations of lupus erythematosus: results from PAISLEY CLE, a global, randomized, placebo-controlled, phase II trial