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Description

The GIY-YIG domain of GRXS16 alone has endonuclease activity and the activity is decreased substantially in GRXS16 (Liu et al., 2013)

SARS-CoV-2 infection: NLRP3 inflammasome as plausible target to prevent cardiopulmonary complications

Changing the length of the trigger internal loop (that is, the length of the target fragment bridging the two paired regions of the target site), and thereby presumably altering the distal miRNAtrigger duplex trajectory, substantially reduced ZSWIM8 binding and polyubiquitylation (Extended Data Fig