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They found that microbial -diversity decreased as the duration of illness increased, meaning that the variety of gut bacteria reduced over time in individuals with BD (Painold et al., 2019)

however, the additional modes employed in combination therapy, although theoretically promising, remain under-investigated

doi: 10.1038/onc.2012.635 70 KabirMFMohd AliJHaji HashimO

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For both the wild-type and hepsin / mice treated with 2APB, the survival rate increased significantly compared with the vehicle control group at 72 h post-APAP administration (Fig