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In addition, DMF mediates a time-course-dependent effect to induce DNA hypomethylation on reactive oxygen species (ROS) regulatory genes such as NRF2, CES1-3, GSTA1-5, NOX1-5, NQO1, and TXNRD1 30

Retrieved 27 August 2009

( 3729(b)(1)(A)

2003 Sep 15 [Updated 2021 Jan 28]

Synergy with immune checkpoint blockade In situ cancer vaccination primes broad, patient-specific T-cell responses by releasing diverse tumor antigens and activating antigen-presenting cells, but the efficacy is often limited by immune checkpoints such as PD-1/PD-L1 and CTLA-4 that suppress CTL activity within the TME