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The tirzepatide constipation guide addresses the slightly different GI pattern seen with dual-agonist therapy

[DOI] [PubMed] [Google Scholar] 58.Ferdowsi P.V., Ahuja K.D.K., Beckett J.M., Myers S

doi: 10.1016/j.molcel.2017.05.030 106 ZhangYSwandaRVNieLLiuXWangCLeeHet al

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ATF3 suppresses cholesterol 25-hydroxylase to reduce oxidized cholesterol accumulation and promotes macrophage RCT, thereby limiting foam cell formation (148,208)