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At the same time, excessive ROS could promote the release of inflammatory factors, deplete glutathione, and reduce the activity of antioxidant stress-related proteins such as GPx4, superoxide dismutase, catalase, etc

That said, in published research to date, melanotan II administration has produced minor side effects such as fatigue, nausea, and yawning, and has not been associated with serious adverse events when administered to healthy subjects

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The antioxidants protect the brain from oxidative stress and inflammation, reducing the risk of neurodegenerative diseases and supporting long-term brain health

LHON REFLECT Study Group

Thyroid-associated ophthalmopathy and ferroptosis: a review of pathological mechanisms and therapeutic strategies