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488 Polymorphisms in TNFAIP3 (A20), a DUB that removes K63-linked ubiquitin chains and adds K48-linked chains to signaling intermediates, are associated with SLE

2.4 Charting the data Following initial screening, two reviewers (MWS, AT) extracted three specific components using a standardized form: (i) key elements of the antioxidant supplements, (ii) the most frequently reported outcome measures used to assess therapeutic controversies, and (iii) data evaluating safety and effectiveness of the supplements

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In addition to the classical and known therapy for obesity, which consists of a combination of low-calorie diets and physical activity, researchers are increasingly exploiting new promising nutrient supplements to interrupt the cumulative risk of obesity [113]