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Ultimately, integrating dynamic biomarkers, multi-omics, and artificial intelligence to tailor treatments to individual patient profiles holds the key to finally fulfilling the promise of effectively managing MIRI

FI at m/z 142.1226 formed due to an alpha cleavage of the parent compound between the -carbon and the carbonyl group

ROS can directly attack DNA, causing oxidative damage (Taniguchi et al., 2012), including base damage and single-strand breaks, which can cause DNA to mutate and change structurally (Roy, 2014)

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The presence of high serum bicarbonate could indicate chronic respiratory acidosis [typical of chronic obstructive pulmonary disease (COPD)] or metabolic alkalosis (secondary to vomiting, use of thiazide diuretics, or excess mineralocorticoids) (336)

10.1038/sj.bjp.0702328 216 PariaghS.TaskerK