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It undergoes a two-step cleavage by proteases such as plasmin, cathepsins, and human kallikrein type 2 to form a two-chain, HMW-uPA, which is further cleaved into a proteolytically active LMW-uPA that retains its plasminogen-activating function

instead, they address different phases and aspects of the healing process

This is an extensive compilation of knowledge around the frequently used amino acid promoieties for the safe development of prodrugs to overcome multiple different delivery barriers

10.1016/j.carbpol.2020.116874 45 GaoM.ZhangW.MaY.LiuT.WangS.ChenS.et al (2025)

However, its always recommended to consult with your healthcare professional to ensure safe and effective use