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Some major pathways known to be involved through studies to date include hormones, oxidative stress, cell death and the activation state of microglia (21)

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After 12 weeks of treatment, both ferulic acid and zopolrestat effectively mitigated hyperinsulinemia and hypertension, successfully restoring normal endothelial relaxation responses ( Geranyl acetate, a terpenoid compound, exhibited notable diuretic and anti-hyperuricemic effects in male rats, particularly at a dosage of 100 mg/kg

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In the blood stream and organ tissues, circulation and accumulation of MDA is one of the major contributions to induce oxidative stress resulting in cancer, diabetes, asthma, atherosclerosis and Alzheimers disease (Dalle-Donne et al