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Description

We tested the association between Tier 1 SNPs and MAS and fibrosis in a large well characterized MASLD cohort

Gastroenterology 156 , 722734.e726 (2019)

Ethics declarations Ethics approval and consent to participate This study was performed in strict accordance with the NIH guidelines for the care and use of laboratory animals and approved by the Institutional Ethics Committee of the Faculty of Biochemistry and Biological Sciences (UNL, Santa Fe, Argentine - Acta CE2022-63)

Correspondingly, our study found that ferroptosis induced by FA injection was accompanied by downregulation of system xCT, leading to the depletion of GSH, which in turn decreased the expression of GPX4