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The terminal ileum is the most common site (~70% of cases)

Am J Pathol 24:591609 Suwandinata FS, Bohle RM, Omwandho CA et al (2007) Management of vulvar melanoma and review of the literature

Microscopically, melanotic macules exhibit increased melanin pigmentation within melanocytes and keratinocytes located at the basal layer of otherwise normal stratified squamous epithelium (Fig