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Insulin receptor substrate 2 expression and involvement in neuronal insulin resistance in diabetic neuropathy

Karimipour M, Rahbarghazi R, Tayefi H, Shimia M, Ghanadian M, Mahmoudi J, Bagheri HS

A favorable vote initiates a formal rulemaking process that typically takes 12 to 24 months before a final rule could take effect

Another study showed that ferroptosis occurs in the hippocampus of db/db mice, and liraglutide, a drug approved for the treatment of obesity and diabetes, reduces ferroptosis by suppressing oxidative stress and iron overload, improving hippocampal neuronal and synaptic plasticity, thereby restoring cognitive impairment (105)

The safety record is generally placebo-like, but several specific findings deserve attention

Tyagi et al., 2024)