glutathione orac NOX-like ROS production by reductase: iScience Reaction schemes involved in Oxygen

This bivalent effect of aminothiols (pro-oxidant and antioxidant), confirmed for in vitro LDL oxidation (Halvorsen et al, 1996), might explain the discrepancies observed between moderate and severe hyperhomocysteinemia

Gamma-glutamyltranspeptidase expression regulates the growth-inhibitory activity of the anti-tumor prodrug gamma-L-glutaminyl-4-hydroxy-3-iodobenzene

To address the reactivities of the redox-sensitive cysteinyl residues, we also analyzed the recombinant monothiol roGFP2 variants roGFP2 C151S and roGFP2 C208S and detected small but reproducible glutathionylation-dependent changes of fluorescence at both excitation wavelengths for roGFP2 C151S (SSG) and roGFP2 C208S (SSG) (Fig

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Acetyl-CoA and the regulation of metabolism: mechanisms and consequences

Atypical methionine sulfoxide reductase B Methionine sulfoxide reductases (MSR) catalyse the reduction of methionine sulfoxide (MetSO), repairing ROS-induced damage to proteins (Fig