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Bioassay of the serum for thyroid-stimulating activity gave a TSH-type response.* These patients were studied in cooperation with Dr

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The production of antibodies against Tg can be induced by massive destruction of the thyroid gland, but high Tg levels in blood do not per se induce antibody production ( 2 levels, and supernormal TSH levels, the anti-Tg antibody titers become abnormal ( 2 induced antibody production in 820% of subjects, together with intra-thyroidal lymphocyte infiltration in some of the patients ( 2 content

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