Enriched with White Truffle Extract, Centella Asiatica, and several antioxidants, the serum contributes to giving the skin a healthy glow and a fresh appearance
Abbreviations XSJ: Xiasangju MASH: Metabolic dysfunction associated steatohepatitis MASLD: Metabolic dysfunction-associated steatotic liver disease CDAHFD: Choline-deficient, L-amino acid-defined, high-fat diet UPLC-Q-TOFMS: Ultrahigh performance liquid chromatography with quadrupole time-of-flight mass spectrometry TCM: Traditional Chinese medicine ECM: Extracellular matrix HSC: Hepatic sellate cell -SMA: Alpha smooth muscle actin Col1a1: Collagen type I alpha 1 TGF-1: Transforming growth factor beta 1 Smad3: Mothers against decapentaplegic homolog 3 PI3K: Phosphoinositide-3 kinase AKT: Protein kinase B Hmox1: Heme oxygenase 1 Nrf2: Nuclear factor erythroid 2-related factor 2 ALT: Alanine aminotransferase AST: Aspartate aminotransferase TC: Total cholesterol TG: Triglycerides MDA: Malondialdehyde SOD: Superoxide dismutase CAT: Catalase GSH-Px: Glutathione peroxidase IL-1: Interleukin-1 IL-6: Interleukin-6 TNF-: Tumor necrosis factor- GO: Gene ontology KEGG: Kyoto encyclopedia of genes and genomes RT-qPCR: Real-time quantitative polymerase chain reaction PLS-DA: Partial least squares discriminant analysis DMs: Differential metabolites DEGs: Differentially expressed genes Msmo1: Methylsterol monooxygenase 1 Cyp51: Cytochrome P450 51 Sqle: Squalene monooxygenase PCSK9: Proprotein convertase subtilisin/kexin type 9 Batf: Basic leucine zipper ATF-Like transcription factor Ticam2: Toll-interleukin 1 receptor domain containing adaptor protein 2 Trim29: Tripartite motif-containing 29 Timp4: Tissue inhibitor of metalloproteinases 4 Thbs1: Thrombospondin 1 Mthfd2: Methylenetetrahydrofolate dehydrogenase 2 PPI: Proteinprotein interaction References Miao L, Targher G, Byrne CD, Cao Y-Y, Zheng M-H
This improves their quality of life
These results indicate PTEN as key player both in nerve regeneration and pain
Berwanger, O
A novel cognitive impairment mechanism that astrocytic p-connexin 43 promotes neuronic autophagy via activation of P2X7R and down-regulation of GLT-1 expression in the hippocampus following traumatic brain injury in rats
