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Linking alpha-synuclein phosphorylation to reactive oxygen species formation and mitochondrial dysfunction in SH-SY5Y cells

Le Fol, V

Ludwig DS, Apovian CM, Aronne LJ, Astrup A, Cantley LC, Ebbeling CB, et al

Bilirubin: CRC

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The ROS produced upon engagement of these receptors can then alter downstream signaling by oxidizing specific cysteine residues within a variety of intracellular proteins including protein kinases, protein phosphatases, adaptor proteins, calcium channels, and transcription factors