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et al: Nature Med

Secondary endpoints include pre-LT AFP levels and complete tumor necrosis on explant histology among patients who received LT

This involves suppression of hippocampal microglial activation and astrocytic hyperplasia, restoration of cytokine homeostasisshifting from a pro- to an anti-inflammatory milieuand enhancement of brain-derived neurotrophic factor (BDNF) expression and AMPA receptor functionality