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Twenty-four obese males, aged 18-50 yrs, with body mass indexes greater than 30 kg/m2 and waist/hip ratios greater than 0.95, were treated with MK-677 25 mg (n = 12) or placebo (n = 12) daily for 8 weeks

Protein homeostasis impairment alters phenotypic heterogeneity of biofilm communities

What is biologically interesting is not yet clinically justified In medicine, "biologically interesting" and "clinically justified" are not the same statement

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At initial presentation, depigmented white macules were localized on the skin of the periorbital and perioral areas, neck and upper chest, hands, axillae and medial surfaces of the thighs (Figure 1A, 2, 3, 4 and B)