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[31] No allergic effects against OHCbl were seen in a study at dosages below 2.5 gm although higher dosages from 5 g to 7.5g showed effects in few volunteers ranging from itching, facial erythema, swelling, eye reddening, shivering, dyspnoea, facial oedema, and spontaneous exanthema

The UK-wide survey, which ran between June 26, 2020, and October 5, 2020, fielded 683 responses

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"If the cracks are accompanied by a sore tongue its a less common sign of a vitamin B deficiency