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N4-hydroxyation of sulfamethoxazole by cytochrome P450 of the CYP2C subfamily and microsomal reduction of its hydroxylamine metabolite in human and rat hepatic microsomes

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Identification of Key Amino Acids Responsible for the Substantially Higher Affinities of Human Type 1 3-Hydroxysteroid Dehydrogenase/isomerase (3-HSD1) for Substrates, Coenzymes, and Inhibitors Relative to Human 3-HSD2

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