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Kim M, Correa AM, McLaughlin P, Erasmus JJ, Moran C, Hofstetter WL, Mehran RJ, Rice DC, Walsh GL, Vaporciyan AA, Swisher SG , Roth JA

A randomized, open-label, parallel pilot study investigating metabolic product kinetics of the novel ketone ester, bis-hexanoyl (R)-1,3-butanediol, over one week of ingestion in healthy adults

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The recovery phase varies from hours to days, and patients are slowly able to resume oral intake and return to baseline

Mitochondria also generate increased levels of reactive oxygen species (ROS), which elevate intracellular oxidative stress, damaging cell membranes, proteins, and DNA, thereby accelerating the aging process

Ferroptosis suppressor protein 1 (FSP1) and coenzyme Q(10) cooperatively suppress ferroptosis