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CpG islands are defined as having more than 500 bp and a GC content of more than 55% with an observed CpG/expected CpG ratio of 0.65

10.3390/antiox9040347 Antioxidants 6 BakallB.FolkJ

CYP450 includes subtypes such as CYP17, CYP19, CYP21, and CYP11A, which are key enzymes in the steroid hormone biosynthesis pathway (Zhai et al., 2023)

Other hormones influenced by gut bacteria metabolites include leptin, ghrelin and insulin

Norethisterone is also partially metabolised into ethinyl oestradiol in the body, meaning combining it with a pill that already contains synthetic oestrogen adds an unpredictable level of hormonal exposure

TLR9 is often responsible for detecting dsDNA that is found in endosomes [121]