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Other measures to target hypoxia include targeting hypoxia-induced signaling pathway proteins (such as HIF-PHD-pVHL pathway proteins and mTOR pathway proteins, etc.) and increasing oxygen supply through vascular normalization (such as the use of antiangiogenic drugs, etc.) (198200) ( Figure 3 )

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MYB, myeloblastosis transcription factors

6 FR autoantibodies (FRAs) have been linked to CFD in cases with 4 and without 6 ASD and also in gestations with neural tube defects 23 and subfertile women

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No published human pharmacokinetic programme was identified