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Targeting sterile inflammation Whether sterile inflammation promotes the progression of liver injury or serves as a means of cellular defense against toxicity remains controversial

Cell 2021;184:19902019

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In polyhexamethylene guanidine-induced pulmonary fibrosis mice, esculetin (10 mg/kg) antagonizes macrophage infiltration, ameliorates alveolar epithelial barrier disruption and reduces the levels of MMP-9, macrophage inflammatory protein 2, IL-8 and IL-1 (82)

Regulation of T cell receptor gene assembly by a complex hierarchy of germline J promoters

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