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Further, inflammasome, in particular NLR family pyrin domain containing 3 (NLRP3) inflammasome is thought to be involved in fibroblasts [147, 148], endothelial cells, and macrophages activation in SSc [149]

If NADH is not reoxidized by methemoglobin, however, pyruvate is reduced in the lactate dehydrogenase (LDH) step, forming lactate as the final end product of glucose metabolism

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This gene provides instructions for making a protein called copper-transporting ATPase 2, which plays a role in the transport of copper from the liver to other parts of the body