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Description

Similarly, miR-139-5p transcriptionally suppresses SLC7A11 to induce ferroptosis and inhibits the proliferation, invasion, and metastasis of PDAC cells [64]

Epub 2015/03/20

Transgenic mice overexpressing human SOD1 with a glycine to alanine mutation in position 93 (mutant-SOD1 mice) have shown to develop selective motor neuron degeneration resembling FALS-like phenotype, which is linked to SOD1 mutations in 1525% of cases (Gurney et al., 1994)