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Ferroptosis suppression contributes to resistance in BRCA-wild-type cancers, while PARPi-FIN combinations synergistically enhance cytotoxicity in BRCA-proficient ovarian cancer models both in vitro and in vivo

It is expected that such tolerance may not be critical as GHK-Cu exists naturally in human body

According to crystallographic data, 28 interface residues from chain A and 29 interface residues from chain B form the inter-subunit contact (Cameron et al., 1995)