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Importantly, the sgRNAs used did not generate off-target mutations across the genome, as confirmed by whole-genome sequencing (Supplementary Fig

Morbidity and mortality at 3 months The proportion of patients attaining a positive outcome was comparable between the intervention and control groups, with 73.68% (14 patients) and 76.19% (16 patients), respectively (95% CI 24.3 to 29.4

Ruminococcaceae are capable of generating short-chain fatty acids, which could inhibit the growth and reproduction of pathogenic intestinal bacteria by impacting the intestinal pH, which is a prerequisite and guarantee for achieving a good growth performance in broilers (69, 70)

This presents clinically as an MI patient who gets worse after treatment

Pastore A, Noce A, Di Giovamberardino G, De Stefano A, Calla C, Zenobi R,