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Because ER redox state strongly affects protein folding, when disulfide bond production is regulated in response to ER stress, luminal oxidative stress rises, and ER function falls [21]

Mol.Cell Biol

doi: 10.1007/1642018154 87 CinarogluMYilmazerE

Introduction Diabetic Kidney Disease (DKD) is one of the most serious microvascular consequences of type 2 diabetes

Discussion Using the Burden of Proof approach, we re-evaluated doseresponse relationships between current alcohol use and risks of 20 health outcomes, finding both harmful and protective associations