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Due to its implication in various cellular processes, ranging from energy production to nucleotide biosynthesis, glutamine has been of growing interest in cancer biology research, where it has been shown to support the aberrant growth and survival mechanisms of cancer cells [7,8,9]

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Inter-relations of folic acid and vitamin B 12 in drug-treated epileptic patients

This defect limits the utilization of alternative energy substrates and reduces overall metabolic flexibility (125)

These findings suggest that AML12 cells exhibit resistance to ferroptosis