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Peer review Peer review information Nature Medicine thanks Christiana Kartsonaki, Peter Rossing, Naveed Sattar and Vikas Sridhar for their contribution to the peer review of this work

In line with the UKB cohort data (ESM Table 9), vitamin B 12 deficiency was more prevalent in the AA genotype group treated with metformin vs GG (OR 2.17 [95% CI 1.80, 2.60]

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Five standard drinks are metabolized in about how many hours