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Description

The curve is somewhat asymmetrical because the steady increase in the volume of the solution during the titration causes the solution to become more dilute

"Paradoxical Vitamin B12 Deficiency: Normal to Elevated Serum B12, With Metabolic Vitamin B12 Deficiency"

Before synthetic vitamin B12 supplements in the late 1940s, anemia caused by vitamin B12 deficiency was treated with liver therapy involving eating raw or partially cooked liver three times a day, or receiving liver injections