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Microscopy From rats, at end of the experiment, the brain, liver, kidney, stomach, duodenum, jejunum, colon, rectum, lungs, and heart were fixed in 10% neutral buffered formalin (pH 7.4) at room temperature for 24 h

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The patients chronic, nonspecific symptomsincluding fatigue, musculoskeletal pain, paresthesia, cognitive disturbances, and optic neuritiswere misattributed to multiple conditions for nearly a decade, with the absence of classic hematologic findings further complicating the diagnosis