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ludwiggi protects against DSS-induced colitis by enhancing the choline/7nAChR-mediated dendritic cell immune tolerance, leading to increased Foxp3 + Treg differentiation ( + dendritic cells from Enterobacter ludwiggi -treated mice exhibited higher expression of tolerogenic markers Tgfb1, Tgfb2, Aldh1a2 , and Pdl1 , and co-culture with nave CD4 + T cells enhances Treg conversion ( Enterobacter ludwiggi exhibited reduced colitis severity and expanded Treg populations in the mesenteric lymph nodes and spleen, highlighting cholines role in shaping gut-immune interactions

A sterile syringe for mixing (typically a 3mL or 5mL syringe with a 21g needle)

FEMS Microbiol Rev 45:fuab033 Gonzalez-Magana A, Altuna J, Queralt-Martin M, Largo E, Velazquez C, Montanchez I, Bernal P, Alcaraz A, Albesa-Jove D (2022) The P

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By evaluating the characteristics of a patient's gut microbiota, more suitable cardiovascular drugs and dosages can be selected for their specific needs, thereby improving treatment effectiveness and reducing side effects

doi: 10.1016/j.jhep.2019.04.007 83 SunKShenYXiaoXXuHZhangQLiM