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Figure 2 Current evidence supports a model in which NRN1 functions as a multifaceted signaling molecule that engages diverse receptor systems and intracellular pathways, as can be seen in Figure 2

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Consistently, the UUO-induced upregulation of fibrosis marker (fibronectin, collagen-1, and -SMA) protein expression echoed the immunofluorescence results and was attenuated in GPX4-OE mice (Fig

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