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While prior studies have focused on SNHG9 s role in microbiota-host crosstalk within the intestine, where it regulates lipid absorption and cell proliferation through SIRT1-dependent mechanisms 9,11 , our findings reveal a tissue-specific mechanism in the liver

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Another model, developed using the gradient boosting algorithm with microbial extracellular vesicle-analysed data as input, has exhibited the highest specificity, sensitivity, and AUC, achieving values of 1.000, 0.936, and 0.993, respectively [189]

It has also been reported that elevated levels of Akkermansia muciniphila might be accountable for the increased levels of shikimate in GBM patients compared to the controls [184, 190, 191]