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Cerebral blood flow in neonatal mice has been reported to be 54 mL/100 g/min ( C 1 is the plasma concentration and the driver of 7,8-DHF brain distribution

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Whilst the side chains of R131 and Q127 in helix 3 assumed relatively fixed positions across the 19 ligand-bound structures, the side chains of E106 and R102 in the antiparallel helix 2 showed more conformational heterogeneity (Fig