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Chronic administration of a Ca 2+ stabilizer, dantrolene, reduced neurological symptoms of SCA3 transgenic mice [158], suggesting that mutant ATXN3-mediated dysregulation of Ca 2+ signaling plays a role in pathogenesis

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However, endplate defects, e.g., Schmorls nodes, were noted more frequently

Reports of side effects with BPC-157 Rapid are rare, and it is typically well tolerated