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More recently, dual AAV-LNP approaches for prime editing have shown promise: scAAV-delivered pegRNAs combined with LNP-encapsulated PE7 mRNA achieved 20.7% correction of the Pah enu2 mutation in phenylketonuria mice, reducing blood phenylalanine below therapeutic thresholds [315]

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Mouse submandibular glands were exposed to a single dose of 15 Gy gamma radiation delivered by a 137 Cs radiation source, using a brain-slit collimator to target radiation to the glands as described previously 51,52,56

Bucillamine in the treatment of patients with mild to moderate COVID-19: an interview with michael frank

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