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research focuses on the effects of short-term exposures or low-concentration exposures on aquatic organisms, and long-term ecological monitoring of SSRIs is rarely performed, and there have been few cross-species studies that have investigated the effects of short-term or low-concentration exposure on aquatic organisms

found that the S1PR2 antagonists modulate the RhoA/ROCK1/Drp1 signaling pathway, reversing high glucose-induced mitochondrial fission, improving endothelial cell migration, and inhibiting apoptosis ( Therefore, dysregulation of mitochondrial dynamics plays an essential pathological role in diabetic wound healing ( 1.4 Mitochondrial apoptosis in diabetic wound healing Apoptosis, a genetically controlled, process of programmed cell death, plays a critical role in tissue homeostasis by rapidly removing excess or damaged cells

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